Choline bitartrate( —— )

Catalog No. M19212 CAS No. 87-67-2

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Product Name

Choline bitartrate
Note

Research use only, not for human use.
Brief Description

Choline bitartrate is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acetylcholine, a chemical that facilitates communication between the nerves and muscles.
Description

Choline bitartrate is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acetylcholine, a chemical that facilitates communication between the nerves and muscles.
In Vitro

Choline serves as a precursor component to two major cell membrane components: phosphatidylcholine and sphingomyelin in vitro.Choline is also a major source for methyl groups via its metabolite, betaine, which participates in S-adenosylmethionine synthesis pathways.
In Vivo

Choline bitartrate (oral gavage; 300 mg/kg vs. 5 g/kg) is administrated. Choline restriction (300 mg/kg) provokes robust ketosis and weight loss in mice, also causes significant hepatic steatosis, inflammation, and cellular injury. when Choline is repleted, moderate ketosis and hepatic fat accumulation can be attenuated.
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Indication

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